Cellblockistry in serous effusion cytology- A systematic review with recent concepts

Review Article

Author Details : Keerthika Sri, Anandraj Vaithy*, Uma Devi, Sowmya

Volume : 6, Issue : 3, Year : 2021

Article Page : 165-169


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Serous effusion cytology being a minimally invasive, readily accessible and inexpensive diagnostic procedure. Nevertheless, the accuracy of SEC could vary widely due to the multitude factors including the level of experience of the cytologists Conventional smear has its own limitations with varied efficacy and hence warranting ancillary studies. Cell block has emerged as a paramount and robust platform for sample processing techniques in cytology. Research studies have proved that the efficiency of cytological diagnosis increases by significant margin of 15-20 percent when it is done in conjunction with cell block techniques especially in cases of exudative fluids in picking up crucial cases and based on this, we intended with a novel aim to analyse the accuracy of Serous effusion cytology by combining conventional smear and cell block technique with an attempt to assess the effectiveness of the cell block by our indigenous Modified Bouin’s method.

Cell block method prepared by our indigenous Modified Bouin’s preparation with formalin fixative proved to show high quality significance and hence it could be followed in routine practice across laboratories. Cell block technique is quantitatively superior both standalone as well as in conjunction with conventional smear by improving the effective diagnosis of SEC. Diligent use of cell block technique eliminates the suspicious of malignant category on CS and thereby giving more definite diagnosis and thus it is mandated that combined approach of CB in conjunction with CS should be practiced as binary protocol which proved to have obvious influence on patient management.

Keywords: Conventional smear, cell block, serous effusion cytology, Histopathology

How to cite : Sri K, Vaithy A, Devi U, Sowmya, Cellblockistry in serous effusion cytology- A systematic review with recent concepts. IP J Diagn Pathol Oncol 2021;6(3):165-169

Copyright © 2021 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)

Article History

Received : 05-07-2021

Accepted : 03-08-2021

Available online : 13-09-2021

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