Analytical study of reactive thrombocytosis prevalence in microcytic hypochromic anemia

Original Article

Author Details : Priyadarshini Devendrappa*, Harish S.G

Volume : 5, Issue : 4, Year : 2020

Article Page : 419-423

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Background : In routine hematology blood samples, every now and then when reporting peripheral smears, we come across cases of microcytic hypochromic anemia with increased platelet count more often in iron deficiency anemia.We have to differentiate is it the cases are just reactive thrombocytosis or else we are neglecting any platelet disorders. Iron deficiency is the commonest cause of secondary thrombocytosis.
Aims and Objectives: To know the prevalence of reactive thrombocytosis in microcytic hypochromic anemia cases. To analyze the range of hemoglobin levels and MCV values in which reactive thrombocytosis is more consistent.
Materials and Methods: The study includes 500 blood samples of patients of all the age groups and both the gender with microcytic hypochromic anemia. The samples were scrutinized for the corresponding thrombocytosis by using a hematology analyzer and confirmed by peripheral smear examination. Serum iron studies were done in confirmed samples of microcytic hypochromic anemia with valid thrombocytosis.
Results : Out of 500 cases of microcytic hypochromic anemia analysed 115 cases had associated thrombocytosis. out of which 17(14.78%) cases were males and 98 (85.22%) cases of females showed thrombocytosis. The majority of cases showed mild thrombocytosis which is frequently seen in cases with MCV 60-70 fl and moderate degree of anemia with hemoglobin level 7-9.9g/dl.
Conclusion : The utmost prevalent cause of reactive thrombocytosis in microcytic hypochromic anemia is iron deficiency. It is rational to distinguish between reactive and clonal thrombocytosis. However, the distinction cannot be always made with certainty, and the diagnosis often depends on watching the platelet count over a while. By identifying the etiology of increased platelet count and type of anemia treatment will be ease.

Keywords: Platelet, Anemia, Hemoglobin, Thrombocytosis.

How to cite : Devendrappa P, S.g H, Analytical study of reactive thrombocytosis prevalence in microcytic hypochromic anemia. IP J Diagn Pathol Oncol 2020;5(4):419-423

Copyright © 2020 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (

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