Correlation of FNAC with Histopathology of breast lesions

Original Article

Author Details : Aaisha Anjum Risaldar, Zeenath Begum*, Uzma Alvi

Volume : 5, Issue : 4, Year : 2020

Article Page : 375-380

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Introduction: Breast cancer is a commonest maliganancy of women globally. A papable breast lump is common diagnostic dilemma to surgeons. Fine needle aspiration cytology (FNAC) is simple rapid, accurate diagnostic tool for evaluating palpable breast lumps. Mammography is other screening modality for a breast lump which is routinely used method with simple, low cost with high accuracy.
Aim: To differentiate and categories the breast lesions, and to study the correlation of FNAC with histopathology of palpable breast lumps.
Materials and Methods: one and half year retrospective study carried out from January 2019 to June 2020 in the department of pathology, KBNIMS, Gulbarga. FNAC and Histopathology slides were retrieved and reviewed. All the slides were observed and findings recorded. Mammography findings were retrieved and recorded.
Result: The present study includes 125 cases out of which 101 cases (80.8%) were benign and 24 cases (19.2%) were malignant. Most common benign breast lesion was fibroadenoma (52.4%) and malignant lesion was infiltrating ductal carcinoma (75%). Frequencies of left breast lesions were high compare to right breast lesions. Out of 125 cases FNAC, 123 cases (98.4%) correlated with histopathology with sensitivity of 91.66%, specificity of 100%, positive predictive value (PPV) of 100%, negative predictive value (NPV) of 98% and accuracy of 98.4%.Out of 125 cases, mammography of 25 cases were retrieved with sensitivity
of 87.5% and specificity of 94.11% with diagnostic accuracy of 92%.
Conclusion: FNAC is a valuable diagnostic tool; provide rapid and reliable diagnosis in breast lesions.

Keywords: FNAC, Benign breast lesions, Malignant breast lesion, Histopathology.

How to cite : Risaldar A A, Begum Z, Alvi U, Correlation of FNAC with Histopathology of breast lesions. IP J Diagn Pathol Oncol 2020;5(4):375-380

Copyright © 2020 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (

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